Squamous Cell Carcinoma
Squamous cell carcinoma (SCC) is the second most common type of skin cancer and develops in squamous cells, which make up the outer layer of the skin. This squamous cell carcinoma definition reflects how the cancer forms when these cells grow abnormally, most often due to long-term sun exposure. According to the American Academy of Dermatology, squamous cell carcinoma frequently appears on areas of the body that receive regular sun exposure, such as the face, ears, lips, neck, hands, and arms.
One of the main answers to what causes squamous cell carcinoma is cumulative ultraviolet (UV) radiation from the sun or tanning beds. SCC can also develop on previously damaged skin, including areas affected by burns, scars, or prior radiation. While many cases grow slowly, squamous cell carcinoma has a higher risk of spreading than basal cell carcinoma if left untreated, making early diagnosis important.
Squamous Cell Carcinoma Symptoms
Squamous cell carcinoma symptoms can vary in appearance and may resemble other skin conditions. Common signs include:
- A hard, scaly, or crusted reddish bump or patch
- An open sore that itches, bleeds, crusts, and returns
- Thick, rough, or scaly patches, especially on the lips
- A lesion that does not heal or continues to change over time
Because there are different types of squamous cell carcinoma, symptoms may vary depending on how deeply the cancer has grown. Any persistent or changing skin lesion should be evaluated by a dermatologist.